I see the concern with Wyatt but I honestly don't know who else it applies to. Parsons is all world regardless (injury recovery TBD and not relevant to scheme). LVN is a stand up edge, Hafley had him doing it last year. Cox arguably is a better stand up edge than pure 4-3 DE, that's sort of what I remember his draft profile saying. Frankly I don't think Gute went out of his way to really commit to that 4-3 front, they never tried to transform themselves into the 49ers front, as an example, personnel wise. Hafley still had both LVN and Gary standing up.
I don't like the Gannon hire overall precisely because I still see too much lack of talent, his success in Philly was player dependent up front, those guys were demons. ML seems to be the only coach who had a problem playing against his D in Arizona, I don't like all that zone stuff especially when CB1 right now is Nixon who has proven to be lazy and poor tracking the ball when it's in front of him.